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An artist rsquo s i adidas sambarose mpression of the GPCR activation from inside the cell and the resulting targeted response. Credit: Kobayashi and Kawakami et al., 2023Scientists have discovered a new way to activate G-protein coupled receptors from inside cells, a breakthrough that helps develop drugs with stanleycup out side effects.Have you ever wondered how drugs reach their targets and achieve their function within our bodies Imagine the drug molecule or ligand as dunks nike store a message, and the cell membrane receptor serving as the inbox. One such receptor tasked with transmitting molecular signals is the G protein-coupled receptor (GPCR).Interestingly, around one-third of all existing drugs work by controlling the activation of this protein. Japanese researchers now reveal a new way of activating GPCR by triggering shape changes in the intracellular region of the receptor. This new process can help researchers design drugs with fewer or no side effects.If the cell membrane is like an Oreo cookie sandwich, GPCR is lik Mgkm Fuji Xerox Suite of Solutions Enable Companies to Be Mobile and Cloud Ready
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